Are you looking for best cold and sinus medicine, we’ve consulted top experts who has in-and-out knowledge about the cold and sinus medicine. We choose the top most quality product, which comes with amazing features you’ve never heard before. We have filter more than 100+ of product to give you top 10 list of best cold and sinus medicine.

This list is undoubtedly the best cold and sinus medicine available in the market today. However, if you don’t want to spend more time on filtering and finding which one is good cold and sinus medicine, then you should absolutely go for our Top list of the winner. which comes with all the basic features one could expect in a cold and sinus medicine.


Best cold and sinus medicine – The Winners!


But these three has some more competitions too, Check out below List of Top 10 best cold and sinus medicine.

If you are ready to choose a new cold and sinus medicine, check out our recommendations for the best cold and sinus medicine. But if you’d like to learn more about the various types of cold and sinus medicine available and how to choose the right one for you, read on.


List of Top 10 Best cold and sinus medicine In Detailed


SaleBestseller No. 1
Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant, 24 Count
  • 24-count box of Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant Tablets provide powerful relief of sinus pain, sinus pressure, nasal congestion and headaches
  • Each caplet contains 5 milligrams of the decongestant phenylephrine HCl and 325 milligrams of acetaminophen, a pain reliever and fever reducer
  • This sinus congestion & pain medicine also temporarily relieves nasal congestion associated with hay fever, upper respiratory allergies and the common cold
  • The non-drowsy decongestant helps promotes sinus drainage, temporarily reduces fever and helps relieve headaches and minor aches and pain
  • From the #1 pharmacist recommended brand among oral OTC decongestants, this maximum strength formula can be used by adults and children 12 years and older for powerful symptom relief
Bestseller No. 2
Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 20 Coated Tablets
  • One package of 20 coated tablets of Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl
  • Advil ibuprofen 200mg pain medicine for adults temporarily relieves fever, minor body aches and headache
  • Phenylephrine HCl 10 mg tablets provide sinus pressure relief, nasal congestion relief and nasal swelling relief
  • Coated tablets are easily portable, so you can have Advil congestion relief ready whenever you need it
  • Nighttime or Daytime sinus medicine for adults and children 12 years and older
  • Take one of these sinus decongestant tablets every 4 hours as needed for symptoms
Bestseller No. 3
Tylenol Sinus + Headache Daytime Non-Drowsy Relief Caplets, Acetaminophen 325mg, Nasal Decongestant for Sinus Pressure, Headache & Nasal Congestion Relief, 24 ct
  • 24-count box of Tylenol Sinus + Headache Daytime Caplets for non-drowsy sinus symptom and headache pain relief due to the common cold, hay fever or other respiratory allergies
  • Pain reliever and nasal decongestant formulated to temporarily relieve symptoms of nasal congestion, sinus headache and pressure
  • Each sinus relief caplet contains 325 mg of acetaminophen to temporarily relieve pain and reduce fever as well as 5 mg of phenylephrine HCl, a nasal decongestant to help clear nasal passages
  • The non-drowsy formula of this sinus medicine provides effective daytime symptom relief by promoting sinus drainage and helping to decongest sinus openings and passages
  • From the #1 doctor-recommended pain relief brand, these daytime headache and sinus relief caplets are suitable for adults and children ages 12 years and older
SaleBestseller No. 4
Alka-Seltzer Plus Maximum Strength PowerMax Sinus Congestion and Pain Liquid Gels - Sinus Congestion / Pressure and Pain Relief for Adults and Children 12 Years and Older, 24 Count
  • Alka-Seltzer Plus Maximum Strength Sinus Congestion and Pain relieving Powermax gels provide powerful fast relief *Use as directed.
  • Alka-Seltzer Plus Maximum Strength PowerMax Sinus Congestion and Pain Liquid Gels provide fast relief from symptoms due to a cold or flu.
  • The sinus congestion and pain liquid gels formula offers relief from minor aches and pains, fever, headache, cough, sore throat, nasal and sinus congestion.
  • Relieve your worst symptoms of nasal & sinus congestion, headache, body pain and cough with Alka-Seltzer Plus congestion, pain relief, and sinus medicine for adults and children 12 years and older
  • Alka-Seltzer Plus PowerMax Sinus Congestion and Pain Liquid Gels contain a combination of pain relievers, cough suppressant, and nasal decongestants to effectively target sinus congestion, pain, fever, cold and flu symptoms
  • Packaging may vary
SaleBestseller No. 5
Alka-Seltzer Plus Maximum Strength PowerMax Sinus Congestion & Pain Medicine, Day + Night Liquid Gels - Powerful Relief for Cold and Flu, Sinus Congestion for Adults and Children 12+ Years, 24 Count
  • Alka-Seltzer Plus Maximum Strength sinus, congestion and pain Powermax gels provide powerful fast relief *Use as directed.
  • Sinus, congestion and pain relief Day and Night liquid gels should not be taken at the same time; Wait 4 hours after the last Night dose before starting Day product.
  • Powerful relief, day or night, from your worst sinus, cold and flu symptoms
  • Day time formula provides relief from fever, headache, nasal congestion, sinus congestion / pressure, minor aches and pains, cough, and sore throat. In addition to these symptoms, the Night-time formula also helps relieve runny nose & sneezing.
  • Alka-Seltzer Plus Maximum Strength PowerMax Sinus Congestion and Pain Medicine is a powerful cold and flu medicine for adults and children 12 years and older.
  • Packaging may vary
Bestseller No. 6
Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count
  • 24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. From the #1 doctor recommended pain relief brand, the combo pack includes 16 Daytime and 8 Nighttime caplets for relief any time of the day
  • The Daytime relief caplets are formulated to reduce fever, loosen phlegm and relieve headache, body aches, cough, sore throat, nasal congestion and chest congestion
  • The Nighttime relief caplets help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion and pressure
  • Each cold & flu caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant
  • The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make coughs more productive. The Nighttime caplets also contain 2 mg of chlorpheniramine maleate, an antihistamine.
SaleBestseller No. 7
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.
  • 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
Bestseller No. 8
Mucinex Fast-Max Day Time Cold & Flu and Night Time Cold & Flu Liquid Medicine, 12 fl oz, Maximum Strength All in One Multi Symptom Relief for Congestion, Sore Throat, Headache,Cough and Reduces Fever
  • MUCINEX FAST-MAX: Maximum strength multi-symptom relief medicine; 1 dose treats 9 symptoms - get back to what’s important thanks to the fast, powerful relief of Mucinex
  • DAY TIME SYMPTOMS TREATED: Maximum strength day time cold and flu non-drowsy liquid relieves cough, chest, nasal & sinus congestion that can cause mucus buildup, sinus pressure, fever, body pain & headache and sore throat
  • NIGHT TIME SYMPTOMS TREATED: Maximum strength night time cold and flu liquid relieves cough, nasal congestion that leads to stuffy nose, fever, body pain & headache, sneezing, runny nose and sore & itchy throat
  • DAY TIME ACTIVE INGREDIENTS per 20 mL: Acetaminophen - 650 mg pain reliever and fever reducer; Phenylephrine HCI - 10 mg nasal decongestant; Dextromethorphan HBr - 20 mg cough suppressant; Guaifenesin - 400 mg expectorant/thins and loosens mucus
  • NIGHT TIME ACTIVE INGREDIENTS per 20 mL: Acetaminophen - 650 mg pain reliever and fever reducer; Phenylephrine HCI - 10 mg nasal decongestant; Diphenhydramine HCI - 25 mg cough suppressant/antihistamine
  • FAST ACTING LIQUID: 2 bottles 6 fl oz each; adults and children 12 years of age and older, 20 ml in provided dosing cup every 4 hours
  • TRUST MUCINEX: Mucinex is the #1 Cold & Cough Brand Doctors Trust for Themselves & Their Families
  • FSA & HSA ELIGIBLE: Save up to 30%. Cover your out-of-pocket expenses with pre-tax dollars.
SaleBestseller No. 9
Alka-Seltzer Plus Maximum Strength Power Max Sinus, Allergy and Cough Medicine for Adults and Children 12 Years and Older - Relieves Symptoms from Allergies, Colds or Hay Fever, 24 Count
  • Alka-Seltzer Plus Maximum Strength Powermax gels provide powerful allergy and sinus relief *Use as directed.
  • Get the fast, effective relief from colds, hay fever, and allergy symptoms when you need it.
  • ASP Sinus, Allergy & Cough medicine contains a pain reliever / fever reducer, cough suppressant, antihistamine and a nasal decongestant.
  • This sinus, allergy, and cough medicine contains an antihistamine which helps to reduce allergy symptoms like sneezing, runny nose, and itchy/watery eyes.
  • This Sinus, Allergy & Cough relief medicine also contains cough suppressant and nasal decongestant to help relieve cough, nasal congestion, sinus congestion and pressure.
  • Packaging may vary
SaleBestseller No. 10
Vicks Sinex SEVERE LiquiCaps, All-In-One Sinus Relief, Non-Drowsy, Nasal Decongestant, Maximum Strength Relief of Sinus Headache, Pain, Pressure, & Congestion, 24 LiquiCaps
  • Experience fast; powerful relief from nasal congestion; sinus pressure; sinus headache; and sinus pain!
  • Best suited to treat sinus symptoms caused by the common cold; hay fever; or other upper respiratory allergies because it reduces pressure in the sinuses and relieves sinus pain!
  • The powerful; non-drowsy nasal decongestant medicine and pain reliever help to provide all in one relief for your sinus symptoms!
  • HSA and FSA eligible; Check with your provider for more details
  • This product is not formulated with an antihistimine allergy medicine and is not intended to treat runny nose; itchy & watery eyes; or sneezing

Hope this list of the best cold and sinus medicine will be helpful for you. Feel free to contact us if you have any questions about our site or our reviews, and we will be happy to help you with your purchasing decisions in any way we can.